As part of the deal between Marvel Studios and Audi, the fourth generation of A8 first premiered in the "Driver's Test" commercial that premiered on June 19, 2017, as a tie-in to Spider-Man: Homecoming movie. In the commercial, Peter Parker (Tom Holland) takes the car, a prototype belonging to Tony Stark, for a test-drive alongside his driving instructor played by J. B. Smoove. The car also had a small product placement appearance in the actual movie itself. The first public premiere of the car was at the Audi Summit in Barcelona on July 11, 2017. It will be produced at Neckarsulm plant. The Audi Prologue concept is a preview of this car.

It will be the first car in the world to have Level 3 autonomous driving - capable of self-driving at speeds up to 60 km/h (37 mph) and self-parking.

In the interiors, the buttons will be replaced with a touch screen.

The gasoline engines will be 3.0 TFSI V6 with 340 PS, 4.0 TFSI V8 with 460 PS and a 6.0 TFSI W12 from Bentley Bentayga, detuned to 585 PS. Diesel engines will be 3.0 TDI V6 with 286 PS and lifted from Audi SQ7 and Bentley Bentayga Diesel, the 4.0 TDI V8 with 435 PS. Like the previous generation, all cars will feature all-wheel drive and 8-speed Tiptronic automatic.

The new A8 will go on sale in September 2017. Estimated UK price is £70,000.